Scott L Jr, Fender AC, Saljic A, Li L, Chen X, Wang X, Linz D, Lang J, Hohl M, Twomey D, Pham TT, Diaz-Lankenau R, Chelu MG, Kamler M, Entman ML, Taffet GE, Sanders P, Dobrev D, Li N. NLRP3 Inflammasome Is a Key Driver of Obesity-Induced Atrial Arrhythmias. Cardiovasc Res. 2021. 117:1746-1759.  

Heijman J, Muna P, Veleva T, Molina CE, Sutanto H, Tekook M, Wang QL, Abu-Taha IH, Gorka M, Kunzel S, El-Armouche A, Reichenspurner H, Kamler M, Nikolaev V, Ravens U, Li N, Nattel S, Wehrens XH, Dobrev D. Cardiomyocyte NLRP3-inflammasome and Calcium/Calmodulin-dependent Kinase II Signaling Create a Cellular Substrate for Post-operative Atrial Fibrillation. Circ Res. 2020.127:1036-55.  

Greer-Short A, Musa H, Alsina KM, Ni L, Word TA, Reynolds JO, Gratz D, Lane C, El-Refaey M, Unudurthi S, Skaf M, Li N, Fedorov VV, Wehrens XHT, Mohler PJ, Hund TJ. Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia. Heart Rhythm. 2020. 17:503-511. 

 

Fender AC, Kleeshulte S, Stolte S, Leineweber K, Kalmer M, Bode J, Li N, Dobrev D. Thrombin Receptor PAR4 Drives Canonical NLRP3 Inflammasome Signaling in the Heart.  Basic Res Cardiol. 2020. 115:10. 

Zhang M, Hill MC, Kadow ZA, Suh JH, Tucker NR, Hall AW, Tran TT, Swinton PS, Leach JP, Marguiles KB, Ellinor PT, Li N, Martin JF. Long-range Pitx2c Enhancer Promoter Interactions Prevent 1 Predisposition to Atrial Fibrillation. Proc Natl Acad Sci U S A. 2019.116: 22692-22698. 

Alsina KM, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L Jr, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Lehnart SE, Wehrens XHT. Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation. Circulation. 2019. 140:681-693.

Ni L, Scott L Jr, Campbell HM, Pan X, Alsina KM, Reynolds J, Philippen LE, Hulsurkar M, Lagor WR, Li N, Wehrens XHT. Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector. Circ Res. 2019;124(2):256-262.

 

Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I Dr, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El-Armouche A, Tony Eissa N, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N. Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial FibrillationCirculation. 2018; 138(20):2227-2242.

Chiang DY, Zhang M, Voigt N, Alsina KM, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li NIdentification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation. Int J Cardiol. 2015 Apr 1;184:190-7

 

Chiang DY, Kongchan N, Beavers DL, Alsina KM, Voigt N, Neilson JR, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li NLoss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014 Dec;7(6):1214-22

Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XHT. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25;129(12):1276-1285

 

 

Li N, Wang T, Wang W, Cutler MJ, Wang Q, Voigt N, Rosenbaum DS, Dobrev D, Wehrens XH. Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice. Circ Res. 2012 Feb 3;110(3):465-70

Kim JA, Chelu MG, Li N. Genetics of Atrial Fibrillation. Curr Opin Cardiol. 2021. 36:281-287.

 

Wang X, Chen X, Dobrev D. Li N. The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation. Pflügers Archiv - European Journal of Physiology. 2021. 473:389-405.

 

Li N & Brundel BJ. Atrial Fibrillation Compendium - Inflammasome and proteostasis: Novel Molecular Mechanisms Associated with Atrial Fibrillation. Circ Res. 2020. 127: 73-90. (*Correspondence)

 

Suryavanshi SV, Li N. Behçet's disease: A (silk) route to atrial fibrillation? Int J Cardiol. 2019 Jul 19. pii: S0167-5273(19) 33157-2. [Epub ahead of print]

 

Scott L Jr, Li N, Dobrev D. Role of inflammatory signaling in atrial fibrillationInt J Cardiol. 2018 Oct 4;. doi: 10.1016/j.ijcard.2018.10.020. 

 

Chelu MG, Li NBiomarkers (plasma trimethylamine-N-oxide) to predict atrial fibrillation: Are we there yet?. Int J Cardiol. 2018; 267:116-117 .

 

Chen G, Chelu MG, Dobrev D, Li NCardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications. Front Physiol. 2018;9:1115. doi: 10.3389/fphys.2018.01115. eCollection.

 

Li N, Dobrev D. Targeting atrial fibrillation promoting atrial structural remodeling: is this a viable strategy in patients with heart failure?Naunyn Schmiedebergs Arch Pharmacol. 2018;391(3):231-233.

Li N, Dobrev D. Hyperuricemia: A causal player or a bystander linking inflammatory signaling and atrial fibrillation? Int J Cardiol. 2017; 231:177-178.

Li NEditorial Commentary: The emerging role of epigenetics in atrial fibrillation. Trends Cardiovasc Med. 2016;26(4):319-20.

 

Li N, Dobrev D, Wehrens XH. PITX2: a master regulator of cardiac channelopathy in atrial fibrillation?. Cardiovasc Res. 2016;109(3):345-7

 

 

 

 

Original Research Papers
(selected)
Editorial & Review Articles

For complete publication, please check my NCBI ​bibliography ​

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